35940-03-5

35940-03-5 structure

Name: Antiviral agent 23
Chemical Name: Antiviral agent 23
CAS Number: 35940-03-5
Molecular Formula: C₁₈H₂₁N₅O₄
Molecular Weight: 371.39
Catalog: Research Areas Infection
Create Date: 2023-04-13 18:11:28
Modify Date: 2024-04-05 18:31:48
Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1].

Name	Antiviral agent 23

Description	Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1].
Related Catalog	Research Areas >> Infection
In Vitro	Antiviral agent 23 (0-100 μM) 抑制 CVA21 和 EV68 在 HeLa 细胞中的复制，其 EC50 值分别为 36.4 和 8.9 μM[1]。 Antiviral agent 23 (100 μM) 抑制 METTL3/METTL14 的酶活，至 74.45%[1]。 Antiviral agent 23 (0-100 μM) 抑制 EV71 毒株 BrCr 在 RD 细胞中的复制，EC50 值为 94 nM[1]。
References	[1]. Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942.

Molecular Formula	C₁₈H₂₁N₅O₄
Molecular Weight	371.39