Dodecylphosphocholine-d25

Modify Date: 2024-01-02 13:20:50

Dodecylphosphocholine-d25 structure	Common Name	Dodecylphosphocholine-d25
	CAS Number	861924-55-2	Molecular Weight	351.46200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₃₈NO₄P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dodecylphosphocholine-d25

Dodecylphosphocholine-d25 is the deuterium labeled Dodecylphosphocholine[1]. Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[2][3].

Name	Ethanaminium, 2-[[(dodecyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-d25-oxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Synonym	More Synonyms

Description	Dodecylphosphocholine-d25 is the deuterium labeled Dodecylphosphocholine[1]. Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. de Haas GH, Dijkman R, Ransac S, Verger R. Competitive inhibition of lipolytic enzymes. IV. Structural details of acylamino phospholipid analogues important for the potent inhibitory effects on pancreatic phospholipase A2. Biochim Biophys Acta. 1990;1046(3):249-257. [3]. François Dehez, et al. Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. Biophys J. 2017 Dec 5113(11):2311-2315. [4]. Sarah D Cady, et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc. 2011 Mar 30133(12):4274-84.

Molecular Formula	C₁₇H₃₈NO₄P
Molecular Weight	351.46200
Exact Mass	351.25400
PSA	68.40000
LogP	5.18530

Ethanaminium, 2-[[(dodecyl-d25-oxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

Dodecyl-d25-phosphocholine

Dodecylphosphocholine-d25

Use of Dodecylphosphocholine-d25

Names

Dodecylphosphocholine-d25 Biological Activity

Chemical & Physical Properties

Synonyms