4-Hydroxymethamphetamine (hydrochloride)

Modify Date: 2024-01-03 12:36:35

4-Hydroxymethamphetamine (hydrochloride) structure	Common Name	4-Hydroxymethamphetamine (hydrochloride)
	CAS Number	877-86-1	Molecular Weight	201.693
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₆ClNO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-Hydroxymethamphetamine (hydrochloride)

Pholedrine hydrochloride, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine hydrochloride is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine hydrochloride can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine hydrochloride can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome[1][2][3].

Name	4-Hydroxymethamphetamine (hydrochloride)
Synonym	More Synonyms

Description	Pholedrine hydrochloride, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine hydrochloride is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine hydrochloride can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine hydrochloride can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome[1][2][3].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Peinhardt GP. High-performance liquid chromatographic determination of pholedrine in human serum using ion-pair extraction and amperometric detection. J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):309-12. [2]. A T Bates, et al. Pholedrine: a substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome. J Neurol Neurosurg Psychiatry. 1995 Feb;58(2):215-7. [3]. Richard Bade, et al. Pholedrine is a marker of direct disposal of methamphetamine. Sci Total Environ. 2021 Aug 15;782:146839.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

References

[1]. Peinhardt GP. High-performance liquid chromatographic determination of pholedrine in human serum using ion-pair extraction and amperometric detection. J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):309-12.

[2]. A T Bates, et al. Pholedrine: a substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome. J Neurol Neurosurg Psychiatry. 1995 Feb;58(2):215-7.

[3]. Richard Bade, et al. Pholedrine is a marker of direct disposal of methamphetamine. Sci Total Environ. 2021 Aug 15;782:146839.

Molecular Formula	C₁₀H₁₆ClNO
Molecular Weight	201.693
Exact Mass	201.092041

4-[2-(Methylamino)propyl]phenol hydrochloride (1:1)

Phenol, 4-[2-(methylamino)propyl]-, hydrochloride (1:1)

4-Hydroxymethamphetamine (hydrochloride)

Use of 4-Hydroxymethamphetamine (hydrochloride)

Names

4-Hydroxymethamphetamine (hydrochloride) Biological Activity

Chemical & Physical Properties

Synonyms