SARS-CoV-2 nsp13-IN-4

Modify Date: 2024-01-13 15:49:06

SARS-CoV-2 nsp13-IN-4 structure	Common Name	SARS-CoV-2 nsp13-IN-4
	CAS Number	923140-39-0	Molecular Weight	407.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₅BrN₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SARS-CoV-2 nsp13-IN-4

SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].

Name	SARS-CoV-2 nsp13-IN-4

Description	SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 57 μM (nsp13 ssDNA+ ATPase) [1]
In Vitro	SARS-CoV-2 nsp13-IN-4 (C4 (d)) inhibits the ssDNA+ ATPase activity and the ssDNA− ATPase activity of nsp13 with IC50 values of 57 μM and 240 μM, respectively[1].
References	[1]. Aliakbar Khalili Yazdi, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Molecular Formula	C₂₀H₁₅BrN₄O
Molecular Weight	407.26

SARS-CoV-2 nsp13-IN-4

Use of SARS-CoV-2 nsp13-IN-4

Names

SARS-CoV-2 nsp13-IN-4 Biological Activity

Chemical & Physical Properties