Venlafaxine-d6-1

Modify Date: 2024-01-21 13:01:05

Venlafaxine-d6-1 Structure
Venlafaxine-d6-1 structure
Common Name Venlafaxine-d6-1
CAS Number 940297-06-3 Molecular Weight 283.44
Density N/A Boiling Point N/A
Molecular Formula C17H21D6NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Venlafaxine-d6-1


Venlafaxine-d6-1 is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

 Names

Name Venlafaxine-d6-1

 Venlafaxine-d6-1 Biological Activity

Description Venlafaxine-d6-1 is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

[3]. Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121(1-2):70-5.

 Chemical & Physical Properties

Molecular Formula C17H21D6NO2
Molecular Weight 283.44