Analyst (Cambridge UK) 2015-06-07

Real-time monitoring of H2O2 release from single cells using nanoporous gold microelectrodes decorated with platinum nanoparticles.

Chong Xiao, Yan-Ling Liu, Jia-Quan Xu, Song-Wei Lv, Shan Guo, Wei-Hua Huang

Index: Analyst 140 , 3753-8, (2015)

Full Text: HTML

Abstract

Here, we report a self-supported nanoporous gold microelectrode decorated with well-dispersed and tiny platinum nanoparticles as an electrochemical nonenzymatic hydrogen peroxide biosensor. Nanoporous gold was fabricated by electrochemical alloying/dealloying and then small-sized platinum nanoparticles were electrodeposited uniformly on them. This novel hybrid nanostructure endows the sensor with high sensitivity and selectivity towards the reduction of hydrogen peroxide with a low detection limit of 0.3 nM. The sensor has been successfully applied for the measurement of H2O2 release from a single isolated human breast cancer cell, demonstrating its great potential for further physiological and pathological applications.


Related Compounds

Related Articles:

Evaluation of the immune response and protective efficacy of Schistosoma mansoni Cathepsin B in mice using CpG dinucleotides as adjuvant.

2015-01-03

[Vaccine 33(2) , 346-53, (2014)]

Comparison of mcl-Poly(3-hydroxyalkanoates) synthesis by different Pseudomonas putida strains from crude glycerol: citrate accumulates at high titer under PHA-producing conditions.

2014-01-01

[BMC Biotechnol. 14 , 962, (2015)]

Process development for scum to biodiesel conversion.

2015-06-01

[Bioresour. Technol. 185 , 185-93, (2015)]

Lipid production in the under-characterized oleaginous yeasts, Rhodosporidium babjevae and Rhodosporidium diobovatum, from biodiesel-derived waste glycerol.

2015-06-01

[Bioresour. Technol. 185 , 49-55, (2015)]

Investigation of the interactions between the EphB2 receptor and SNEW peptide variants.

2014-12-01

[Growth Factors 32(6) , 236-46, (2014)]

More Articles...