Journal of Antibiotics 1993-12-01

Synthesis of 3-episiastatin B analogues having anti-influenza virus activity.

Y Nishimura, Y Umezawa, S Kondo, T Takeuchi, K Mori, I Kijima-Suda, K Tomita, K Sugawara, K Nakamura

Index: J. Antibiot. 46(12) , 1883-9, (1993)

Full Text: HTML

Abstract

Two epimers of siastatin B, 3-episiastatin B (3) and 3,4-diepisiastatin B (4), were obtained by the chemical modification of siastatin B. Compound 3 showed marked inhibitory activity against influenza virus neuraminidases and significant inhibition of influenza virus infection in vitro.

Related Compounds

Related Articles:

Contributions of NanI sialidase to Caco-2 cell adherence by Clostridium perfringens type A and C strains causing human intestinal disease.

2014-11-01

[Infect. Immun. 82(11) , 4620-30, (2014)]

Syntheses and activities of N-substituted derivatives of siastatin B.

1992-10-01

[J. Antibiot. 45(10) , 1662-8, (1992)]

Synthesis of the sialidase inhibitor siastatin B.

2007-05-01

[Org. Lett. 2 , 4037, (2000)]

A-72363 A-1, A-2, and C, novel heparanase inhibitors from Streptomyces nobilis SANK 60192, II. Biological activities.

1996-01-01

[J. Antibiot. 49(1) , 61-4, (1996)]

A-72363 A-1, A-2 and C, novel heparanase inhibitors from Streptomyces nobilis SANK 60192. I. Taxonomy of producing organism, fermentation, isolation and structure elucidation.

1996-01-01

[J. Antibiot. 49(1) , 54-60, (1996)]

More Articles...