Analyst (Cambridge UK) 2014-12-07

Rapid identification of synthetic colorants in food samples by using indium oxide nanoparticle-functionalized porous polymer monolith coupled with HPLC-MS/MS.

Ruifang Qi, Xiao Zhou, Xiqian Li, Jiutong Ma, Chunmei Lu, Jun Mu, Xuguang Zhang, Qiong Jia

Index: Analyst 139(23) , 6168-77, (2014)

Full Text: HTML

Abstract

A synthetic protocol for the preparation of an indium oxide nanoparticle-functionalized poly(methacrylic acid-glycidyl methacrylate-ethylene dimethacrylate-ethanediamine) monolithic column is reported. Various techniques, including scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and thermal gravimetric analysis-derivative thermogravimetric analysis were employed to characterize the synthesized monolith. The modified monolithic column was coupled with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) for determining synthetic colorants in various food samples. Under optimized conditions, good linearity was obtained for all the targets with squared regression coefficients greater than 0.9982. The limits of detection (S/N = 3) for 12 synthetic colorants were in the range of 0.012-2.97 μg kg(-1). The intra-day and inter-day relative standard deviations, ranging from 2.7% to 8.5%, were within the acceptable range. The developed method was successfully applied to the determination of synthetic colorants in food samples (candy, milk, jelly, jam, canned food, juice, and carbonated drink). Target recoveries at different spiked levels ranged from 73.5% to 112.1% with relative standard deviations of less than 10.3%.


Related Compounds

Related Articles:

Organic monolith frits encased in polyether ether ketone tubing with improved durability for liquid chromatography.

2015-09-01

[J. Sep. Sci. 38 , 2938-44, (2015)]

Encapsulation of porcine pancreatic islets within an immunoprotective capsule comprising methacrylated glycol chitosan and alginate.

2015-04-01

[J. Biomed. Mater. Res. B. Appl. Biomater. 103(3) , 503-18, (2015)]

Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry.

2014-06-06

[J. Chromatogr. A. 1345 , 17-28, (2014)]

Multifunctional homopolymer vesicles for facile immobilization of gold nanoparticles and effective water remediation.

2014-05-27

[ACS Nano 8(5) , 5022-31, (2014)]

Enantioselective nano liquid chromatographic separation of racemic pharmaceuticals: a facile one-pot in situ preparation of lipase-based polymer monoliths in capillary format.

2014-11-01

[Chirality 26(11) , 754-63, (2014)]

More Articles...