Metal-Based Drugs
1998-01-01
Synthesis, characterization and antitumour activity of metal complexes of 5-carboxy-2-thiouracil.
U P Singh, S Singh, S M Singh
Index: Met. Based Drugs 5 , 35-39, (1998)
Full Text: HTML
Abstract
Metal complexes of 5-carboxy-2-thiouracil with Mn(ll), Co(ll), Ni(ll), Cu(ll), Zn(ll) and Cd(ll) ions were synthesized, characterized, and subjected to a screening system for evaluation of antitumour activity against Sarcoma-180 (S-180) tumour cells. The complexes were characterized by elemental analysis, infrared, electronic spectra, room temperature magnetic measurements and powder X-ray diffraction. The antitumour activity results indicate that some complexes have antitumour activity both in vivo and in vitro against S-180 tumour cells.
Related Compounds
Related Articles:
1982-05-01
[Pharmazie 37 , 355-356, (1982)]