5-Carboxy-2-thiouracil

Names

[ Name ]:
5-Carboxy-2-thiouracil

[Synonym ]:
4-Oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-carbonsaeure
5-Carboxy-2-thiouracil,2-Thiouracil-5-carboxylic acid,5-Carboxy-4-hydroxy-2-thiopyrimidine
1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylicaci
2-thioisoorotic acid
2-Thiouracil-5-carboxylic acid,5-Carboxy-4-hydroxy-2-thiopyrimidine
5-Carboxy-2-thiouracil
1,2,3,4-Tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylic acid
5-Carboxy-7-thiouracil
5-carboxy-2-thio-uracil
1,2,3,4-tetrahydro-4-oxo-2-thioxopyrimidine-5-carboxylic acid
4-oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid
5-carboxy-2-thiouracil free acid
5-CARBOXY-4-HYDROXY-2-THIOPYRIMIDINE

Chemical & Physical Properties

[ Density]:
1.74g/cm3

[ Boiling Point ]:
461.2ºC at 760mmHg

[ Molecular Formula ]:
C₅H₄N₂O₃S

[ Molecular Weight ]:
172.16200

[ Flash Point ]:
232.7ºC

[ Exact Mass ]:
171.99400

[ PSA ]:
122.11000

[ LogP ]:
0.16910

[ Vapour Pressure ]:
2.65E-09mmHg at 25°C

[ Index of Refraction ]:
1.719

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis, characterization and antitumour activity of metal complexes of 5-carboxy-2-thiouracil.

Met. Based Drugs 5 , 35-39, (1998)

Metal complexes of 5-carboxy-2-thiouracil with Mn(ll), Co(ll), Ni(ll), Cu(ll), Zn(ll) and Cd(ll) ions were synthesized, characterized, and subjected to a screening system for evaluation of antitumour ...

[Synthesis and antibacterial and antitumoral activity of some methylhydrazonium salts of pyrimidine bases and their analogues (author's transl)].

Pharmazie 37 , 355-356, (1982)

On reacting pyrimidine metabolites containing a carboxyl or sulfhydryl group with methylhydrazine or N-benzyl-N'-methylhydrazine, various methylhydrazonium salts of these metabolites were synthetized,...