Beilstein Journal of Organic Chemistry 2010-01-01

New library of aminosulfonyl-tagged Hoveyda-Grubbs type complexes: Synthesis, kinetic studies and activity in olefin metathesis transformations.

Etienne Borré, Frederic Caijo, Christophe Crévisy, Marc Mauduit

Index: Beilstein J. Org. Chem. 6 , 1159-66, (2010)

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Abstract

Seven novel Hoveyda-Grubbs precatalysts bearing an aminosulfonyl function are reported. Kinetic studies indicate an activity enhancement compared to Hoveyda's precatalyst. A selection of these catalysts was investigated with various substrates in ring-closing metathesis of dienes or enynes and cross metathesis. The results demonstrate that these catalysts show a good tolerance to various chemical functions.


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