Properties and clinical development of a novel coating technology: the poly[bis(trifluoroethoxy)phosphazene].
Davide Capodanno, Corrado Tamburino
Index: Recent Pat. Drug Deliv. Formul. 4(1) , 18-22, (2010)
Full Text: HTML
Abstract
Ultrapure poly[bis(trifluoroethoxy)phosphazene] is a novel biocompatible, anti-inflammatory, antithrombogenic polymer which has the potential to cover stent devices without elution of a cell cycle inhibiting drug. The properties of polyphosphazene are likely to extend its use to a broad array of promising applications. This article reviews the features of the polymer and some recent patents related to use of poly[bis(trifluoroethoxy)phosphazene] in coating, its relevance as compared to other polymers, current evidence on pre-clinical and clinical performance, and future perspectives.
Related Compounds
Related Articles:
2005-04-01
[Invest. Radiol. 40(4) , 210-8, (2005)]
2007-05-01
[Invest. Radiol. 42(5) , 303-11, (2007)]
Radiation grafting of hydrophilic monomers onto poly[bis(trifluoroethoxy)phosphazene].
1994-09-01
[Biomaterials 15(11) , 937-43, (1994)]
1993-05-01
[Biomaterials 14(6) , 430-6, (1993)]
2009-12-01
[J. Vasc. Interv. Radiol. 20(12) , 1597-607, (2009)]