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MGB-BP-3

Names

[ CAS No. ]:
1000277-08-6

[ Name ]:
MGB-BP-3

[Synonym ]:
1H-Pyrrole-2-carboxamide, 1-methyl-4-[[[1-methyl-4-[[4-[(E)-2-(3-quinolinyl)ethenyl]benzoyl]amino]-1H-pyrrol-2-yl]carbonyl]amino]-N-[2-(4-morpholinyl)ethyl]-
MGB-BP-3
532PWU9738
1-Methyl-4-({[1-methyl-4-({4-[(E)-2-(3-quinolinyl)vinyl]benzoyl}amino)-1H-pyrrol-2-yl]carbonyl}amino)-N-[2-(4-morpholinyl)ethyl]-1H-pyrrole-2-carboxamide
1-methyl-4-({[1-methyl-4-({4-[(E)-2-(quinolin-3-yl)ethenyl]benzoyl}amino)-1H-pyrrol-2-yl]carbonyl}amino)-N-[2-(morpholin-4-yl)ethyl]-1H-pyrrole-2-carboxamide

Biological Activity

[Description]:

MGB-BP-3 is an antibiotic that has been shown to be active against a broad range of important multi-resistant Gram-positive pathogens.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection

[References]

[1]. Fraser J. Scott, et al. An Evaluation of Minor Groove Binders as Anti-Lung Cancer Therapeutics. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3478-86.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
770.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H37N7O4

[ Molecular Weight ]:
631.724

[ Flash Point ]:
419.6±32.9 °C

[ Exact Mass ]:
631.290710

[ LogP ]:
2.44

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.664

Related Compounds