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diazinon (diethyl-d10)

Names

[ CAS No. ]:
100155-47-3

[ Name ]:
diazinon (diethyl-d10)

[Synonym ]:
Oleodiazinon-d10
Diazinon-diethyl-d10
Diazinon-d10
O,O-Bis[(H)ethyl] O-(2-isopropyl-6-methylpyrimidin-4-yl) phosphorothioate
Phosphorothioic acid, O,O-diethyl-d O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] ester
O,O-Bis[(H)ethyl] O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate

Biological Activity

[Description]:

Diazinon-d10 is the deuterium labeled Diazinon[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
353.9±44.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H11D10N2O3PS

[ Molecular Weight ]:
314.407

[ Flash Point ]:
167.9±28.4 °C

[ Exact Mass ]:
314.163818

[ PSA ]:
95.37000

[ LogP ]:
3.81

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
22-50/53

[ Safety Phrases ]:
24/25-60-61

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

Related Compounds