Alfuzosin-d3

Names

[ CAS No. ]:
1006724-55-5

[ Name ]:
Alfuzosin-d3

Biological Activity

[Description]:

Alfuzosin-d3 is deuterium labeled Alfuzosin.

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Wilde MI, et al. Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. Drugs. 1993 Mar;45(3):410-29.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H24D3N5O4

[ Molecular Weight ]:
392.47

Related Compounds