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Bis-PEG9-NHS ester

Names

[ CAS No. ]:
1008402-79-6

[ Name ]:
Bis-PEG9-NHS ester

[Synonym ]:
nhs-dpeg(9)-nhs bis-succinimidyl-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-dioate

Biological Activity

[Description]:

Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Targeting m2-like tumor-associated macrophages by using melittin-based pro-apoptotic peptide. WO2019212324A1

Chemical & Physical Properties

[ Molecular Formula ]:
C30H48N2O17

[ Molecular Weight ]:
708.70500

[ Exact Mass ]:
708.29500

[ PSA ]:
210.43000

[ Storage condition ]:
-20°C


Related Compounds