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Biotin-PEG2-C6-azide

Names

[ CAS No. ]:
1011268-29-3

[ Name ]:
Biotin-PEG2-C6-azide

[Synonym ]:
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[(6-azido-1-oxohexyl)amino]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
MFCD28505538
6-Azido-N-(2-{2-[2-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethoxy]ethoxy}ethyl)hexanamide

Biological Activity

[Description]:

Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H39N7O5S

[ Molecular Weight ]:
513.654

[ Exact Mass ]:
513.273315

[ LogP ]:
-0.63

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds