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RV01

Names

[ CAS No. ]:
1016897-10-1

[ Name ]:
RV01

Biological Activity

[Description]:

RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)
Research Areas >> Inflammation/Immunology

[References]

[1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7.

[2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H13NO2

[ Molecular Weight ]:
263.29

[ Storage condition ]:
2-8°C

Related Compounds