asudemotide

Names

[ CAS No. ]:
1018833-53-8

[ Name ]:
asudemotide

[Synonym ]:
30Q33TZ6A7
L-Isoleucine, L-α-glutamyl-L-tyrosyl-L-tyrosyl-L-α-glutamyl-L-leucyl-L-phenylalanyl-L-valyl-L-asparaginyl-
asudemotide
Isoleucine, L-α-glutamyl-L-tyrosyl-L-tyrosyl-L-α-glutamyl-L-leucylphenylalanyl-L-valyl-L-asparaginyl-
L-α-Glutamyl-L-tyrosyl-L-tyrosyl-L-α-glutamyl-L-leucylphenylalanyl-L-valyl-L-asparaginylisoleucine
L-α-Glutamyl-L-tyrosyl-L-tyrosyl-L-α-glutamyl-L-leucyl-L-phenylalanyl-L-valyl-L-asparaginyl-L-isoleucine
9593

Biological Activity

[Description]:

Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. [1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. H Daiko, et al.Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients. Cancer Immunol Immunother. 2020, 69, 11.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1602.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C58H80N10O17

[ Molecular Weight ]:
1189.313

[ Flash Point ]:
923.0±34.3 °C

[ Exact Mass ]:
1188.570313

[ LogP ]:
3.66

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.586

Related Compounds