Resorcinol (monoacetate)

Names

[ CAS No. ]:
102-29-4

[ Name ]:
Resorcinol (monoacetate)

[Synonym ]:
EINECS 203-022-0
3-Hydroxyphenyl Acetate
Acetic Acid 3-Hydroxyphenyl Ester
Resorcinol Monoacetate
(3-hydroxyphenyl) acetate
MFCD00002266
Resorcinol (monoacetate)

Biological Activity

[Description]:

Resorcinol monoacetate is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and can be used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.223 g/mL at 25 °C(lit.)

[ Boiling Point ]:
283 °C(lit.)

[ Melting Point ]:
129-133 °C

[ Molecular Formula ]:
C₈H₈O₃

[ Molecular Weight ]:
152.14700

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
152.04700

[ PSA ]:
46.53000

[ LogP ]:
1.31750

[ Vapour Pressure ]:
1.81E-05mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.537(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VH2750000

CHEMICAL NAME :: Resorcinol, monoacetate

CAS REGISTRY NUMBER :: 102-29-4

BEILSTEIN REFERENCE NO. :: 1865490

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H8-O3

MOLECULAR WEIGHT :: 152.16

WISWESSER LINE NOTATION :: QR COV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,185,1957 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,185,1957

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H317-H318-H370-H410

[ Precautionary Statements ]:
P260-P273-P280-P305 + P351 + P338 + P310-P308 + P311-P333 + P313

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S36

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
2

[ RTECS ]:
VH2750000

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

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