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PHOME

Names

[ CAS No. ]:
1028430-42-3

[ Name ]:
PHOME

[Synonym ]:
2-Oxiraneacetic acid, 3-phenyl-, 2-amino-1-(6-methoxy-2-naphthalenyl)ethyl ester
2-Amino-1-(6-methoxy-2-naphthyl)ethyl (3-phenyl-2-oxiranyl)acetate

Biological Activity

[Description]:

PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay (extracted from patent CN113402447A)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Chen, Guoliang, et al. sEH inhibitor or pharmaceutically acceptable composition thereof, and preparation method and application thereof.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
564.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H19NO4

[ Molecular Weight ]:
377.433

[ Flash Point ]:
224.4±26.4 °C

[ Exact Mass ]:
377.162720

[ PSA ]:
71.85000

[ LogP ]:
3.79

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.626

Related Compounds