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Artefenomel

Names

[ CAS No. ]:
1029939-86-3

[ Name ]:
Artefenomel

Biological Activity

[Description]:

Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore. Artefenomel (OZ439) is a long-acting artemisinin-related agent[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite
Research Areas >> Infection

[References]

[1]. Phyo AP, et al. Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial. Lancet Infect Dis. 2016 Jan;16(1):61-69.

[2]. Rosenthal PJ. Artefenomel: a promising new antimalarial drug. Lancet Infect Dis. 2016 Jan;16(1):6-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H39NO5

[ Molecular Weight ]:
469.61300

[ Exact Mass ]:
469.28300

[ PSA ]:
49.39000

[ LogP ]:
4.82020

Related Compounds