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Losartan D4

Names

[ CAS No. ]:
1030937-27-9

[ Name ]:
Losartan D4

[Synonym ]:
Losartan-d4
1H-Imidazole-5-methanol,2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]
MK-954-d4
[2H4]-Losartan
2-Butyl-4-chloro-1-[[2 inverted exclamation mark-(1H-tetrazol-5yl)[1,1 inverted exclamation mark-biphenyl-d4]-4-yl]methyl]-1H-imidazole-5-methanol
Cozaar-d4
Losartan D4

Biological Activity

[Description]:

Losartan D4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor
Research Areas >> Others

[Related Small Molecules]

Angiotensin II acetate salt | AVE 0991 | A 779 | Tranilast | PD123319 di(trifluoroacetate) | Telmisartan | Angiotensin II Receptor Ligand | Sacubitril/valsartan (LCZ696) | EMA401 | Fimasartan | (Val5)-Angiotensin II | RE 201 | C-Type Natriuretic Peptide (32-53) (human, porcine, rat) acetate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19D4ClN6O

[ Molecular Weight ]:
426.94

[ PSA ]:
92.51000

[ LogP ]:
4.26680

[ Storage condition ]:
2-8℃


Related Compounds