BAY 80-6946 (Copanlisib)
Names
[ CAS No. ]:
1032568-63-0
[ Name ]:
BAY 80-6946 (Copanlisib)
[Synonym ]:
5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-
2-Amino-N-{7-methoxy-8-[3-(4-morpholinyl)propoxy]-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-5-pyrimidinecarboxamide
Copanlisib
2-Amino-N.N-diaethyl-toluolsulfonamid-(4)
2-amino-toluene-4-sulfonic acid diethylamide
2-Amino-toluol-4-sulfonsaeure-diaethylamid
2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide
BAY 80-6946
BAY 80-6946 (Copanlisib)
Biological Activity
[Description]:
[Related Catalog]:
[Target]
PI3Kα:0.5 nM (IC50)
PI3Kβ:3.7 nM (IC50)
PI3Kδ:0.7 nM (IC50)
PI3Kγ:6.4 nM (IC50)
mTOR:45 nM (IC50)
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Molecular Formula ]:
C23H28N8O4
[ Molecular Weight ]:
480.520
[ Exact Mass ]:
480.223358
[ PSA ]:
146.23000
[ LogP ]:
-1.00
[ Index of Refraction ]:
1.722
[ Storage condition ]:
-20℃