8-Bromotheophylline

Names

[ Name ]:
8-Bromotheophylline

[Synonym ]:
8-bromo-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione
1H-purine-2,6-dione, 8-bromo-3,9-dihydro-1,3-dimethyl-
EINECS 233-846-6
8-BROMOTHEOPHYLLINE
1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl-
8-Bromo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
8-Bromo-1,3-dimethyl-1H-purine-2,6(3H,9H)-dione
8-bromo-1,3-dimethyl-7H-purine-2,6-dione

Biological Activity

[Description]:

8-Bromotheophylline can be used for the synthesis of the Oxazolo[2,3-f]purinediones, which are evaluated for their affinity at adenosine A1 and A2A receptors[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Drabczyńska A, et al. Tricyclic oxazolo[2,3-f]purinediones: potency as adenosine receptor ligands and anticonvulsants. Bioorg Med Chem. 2004;12(18):4895-4908.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
469.5±55.0 °C at 760 mmHg

[ Melting Point ]:
295-297ºC

[ Molecular Formula ]:
C₇H₇BrN₄O₂

[ Molecular Weight ]:
259.060

[ Flash Point ]:
237.7±31.5 °C

[ Exact Mass ]:
257.975220

[ PSA ]:
72.68000

[ LogP ]:
0.08

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.652

MSDS

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Safety Information

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933990090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%