PF-03654746 Tosylate
Names
Biological Activity
[Description]:
PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms[1]. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD)[2].
[Related Catalog]:
[Target]
H3 receptor[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C25H32F2N2O4S
[ Molecular Weight ]:
494.59400
[ Exact Mass ]:
494.20500
[ PSA ]:
98.58000
[ LogP ]:
6.23310