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Benralizumab

Names

[ CAS No. ]:
1044511-01-4

[ Name ]:
Benralizumab

Biological Activity

[Description]:

Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used to treat severe eosinophilic asthma[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[Target]

IL-5Rα[1]


[References]

[1]. Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019 Sep 25;5(3). pii: 00009-2019.

Chemical & Physical Properties

[ Molecular Formula ]:
C6492H10060N1724O2028S42

[ Molecular Weight ]:
146054.0

Related Compounds