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EC-23

Names

[ CAS No. ]:
104561-41-3

[ Name ]:
EC-23

[Synonym ]:
4-[(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)ethynyl]benzoic acid
4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylethynyl)benzoic acid
Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]-
ec 23

Biological Activity

[Description]:

EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[In Vitro]

EC23 (AGN 190205) induces neural differentiation accompanying by elevated levels of stathmin and profilin-1. EC23 induces the expression of known cellular retinoid binding proteins in the TERA2.cl.SP12 cell line[1].

[References]

[1]. Maltman DJ, et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst. 2009 May;5(5):458-71.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
484.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H24O2

[ Molecular Weight ]:
332.435

[ Flash Point ]:
225.8±23.4 °C

[ Exact Mass ]:
332.177643

[ PSA ]:
37.30000

[ LogP ]:
8.21

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds