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Z-Phe-Leu-Glu-pNA

Names

[ CAS No. ]:
104634-10-8

[ Name ]:
Z-Phe-Leu-Glu-pNA

Biological Activity

[Description]:

Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

others


[References]

[1]. Wei Ye, et al. Characterization of the glutamate-specific endopeptidase from Bacillus licheniformis expressed in Escherichia coli. J Biotechnol. 2013 Oct 10;168(1):40-5.  

[2]. Wei Ye, et al. A new strategy for recovery of two peptides without Glu employing glutamate-specific endopeptidase from Bacillus licheniformis. Enzyme Microb Technol. 2014 Jan 10:54:25-31.  

Chemical & Physical Properties

[ Molecular Formula ]:
C34H39N5O9

[ Molecular Weight ]:
661.7

Related Compounds