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PEG12-Tos

Names

[ CAS No. ]:
1050500-41-8

[ Name ]:
PEG12-Tos

[Synonym ]:
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol, mono(4-methylbenzenesulfonate)
35-Hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl 4-methylbenzenesulfonate

Biological Activity

[Description]:

Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
724.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H56O15S

[ Molecular Weight ]:
700.832

[ Flash Point ]:
391.9±32.9 °C

[ Exact Mass ]:
700.333984

[ LogP ]:
-2.99

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.490

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds