5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite

Names

[ Name ]:
5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite

[Synonym ]:
n4-benzoyl-2'-deoxy-5'-o-dmt-5-methylcytidine 3'-ce phosphoramidite
n4-benzoyl-2'-deoxy-5'-o-[bis(4-methoxyphenyl)phenylmethyl]-5-methylcytidine 3'-ce phosphoramidite
5'-o-(4,4'-dimethoxytrityl)-5-methyl-n4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-n,n-diisopropyl)phosphoramidite

Biological Activity

[Description]:

DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Irina V Astakhova, et al. LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding. Bioconjug Chem. 2011 Apr 20;22(4):533-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₅₄N₅O₈P

[ Molecular Weight ]:
847.93400

[ Exact Mass ]:
847.37100

[ PSA ]:
159.99000

[ LogP ]:
8.85158

[ Storage condition ]:
-20℃