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BPH-715

Names

[ CAS No. ]:
1059677-23-4

[ Name ]:
BPH-715

[Synonym ]:
bisphosphonate,15
UNII-YD43M7UAP4
BPH-715
GTPL3196

Biological Activity

[Description]:

BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite
Research Areas >> Infection

[References]

[1]. Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H31NO7P2

[ Molecular Weight ]:
423.37800

[ Exact Mass ]:
423.15800

[ PSA ]:
150.62000

[ LogP ]:
3.61330

Related Compounds