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Procyanidin B-5 3,3'-di-O-gallate

Names

[ CAS No. ]:
106533-60-2

[ Name ]:
Procyanidin B-5 3,3'-di-O-gallate

[Synonym ]:
procyanidin B-5 3,3'-di-O-gallate
procyanidin B4
8)-epicatechin

Biological Activity

[Description]:

Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Abe I, et al. Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis. Planta Med. 2000 Dec;66(8):753-6.  

Chemical & Physical Properties

[ Density]:
1.96g/cm3

[ Boiling Point ]:
1173.4ºC at 760mmHg

[ Molecular Formula ]:
C44H34O20

[ Molecular Weight ]:
882.73

[ Flash Point ]:
355.7ºC

[ Exact Mass ]:
882.16400

[ PSA ]:
354.28000

[ LogP ]:
4.95800

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.915

Related Compounds