Phosphorylcholine

Names

[ CAS No. ]:
107-73-3

[ Name ]:
Phosphorylcholine

[Synonym ]:
Choline phosphate
Choline Phosphoric Acid Ester Chloride
UNII:96AN057F7A
Ethanaminium, N,N,N-trimethyl-2-(phosphonooxy)-, chloride
trimethyl-(2-phosphonooxyethyl)ammonium chloride
Phosphorylcholine Chloride
(2-Hydroxyethyl)trimethylammonium Chloride Phosphate
EINECS 203-516-6
phosphorylcholine
O-Phosphonocholine
O-phosphoryl choline
N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium chloride
N-Trimethyl-2-aminoethylphosphonate
trimethyl[2-(phosphonooxy)ethyl]ammonium chloride
Choline Chloride Dihydrogen Phosphate
choline chloride phosphate
Trimethyl(2-(phosphonooxy)ethyl)ammonium chloride
Ethanaminium, N,N,N-trimethyl-2-(phosphonooxy)-, chloride (1:1)
phosphocholine chloride
o-Phosphocholine

Biological Activity

[Description]:

Phosphorylcholine is an antigenic cell-surface component found on many commensal and pathogenic bacteria that reside in the upper airway.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Cardiovascular Disease

[In Vitro]

Phosphorylcholine materials are bio-inspired polymers that mimic the extracellular surface of red blood cells, containing an exact chemical copy of the predominant zwitterionic phospholipid headgroup found in the cell lipid membrane. The phosphorylcholine side chain of the PC-polymer contains the phosphate moiety present in phosphatidylcholine and phosphatidylserine, the latter being membrane lipid component that is able to bind calcium and is implicated in biomineralization[1].

[References]

[1]. Lawton JM, et al. The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. J Mater Sci Mater Med. 2017 Aug 17;28(9):144.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₅H₁₅ClNO₄P

[ Molecular Weight ]:
219.604

[ Exact Mass ]:
219.042725

[ PSA ]:
76.57000

Safety Information

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%