acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]

Names

[ Name ]:
acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]

[Synonym ]:
Essigsaeure-[2-(5-chlor-2-nitro-phenylmercapto)-anilid]

Biological Activity

[Description]:

PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Neurological Disease

[Target]

PDE7A:2.1 μM (IC50)

[References]

[1]. García AM, wt, al. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors. J Med Chem. 2014 Oct 23;57(20):8590-607.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₁ClN₂O₃S

[ Molecular Weight ]:
322.76700

[ Exact Mass ]:
322.01800

[ PSA ]:
100.22000

[ LogP ]:
4.95400

acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream