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A 61603

Names

[ CAS No. ]:
107756-30-9

[ Name ]:
A 61603

Biological Activity

[Description]:

A-61603 is a selective α1A-adrenergic receptor agonist[1]. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro[2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[Target]

α1A-adrenergic receptor


[References]

[1]. Meyer MD, et al. Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: A novel selective α1A receptor agonist. J. Med. Chem. 39(20), 4116-4119 (1996).

Chemical & Physical Properties

[ Boiling Point ]:
548.4ºC at 760mmHg

[ Molecular Formula ]:
C14H19N3O3S

[ Molecular Weight ]:
309.38400

[ Flash Point ]:
285.5ºC

[ Exact Mass ]:
309.11500

[ PSA ]:
99.17000

[ LogP ]:
2.10350

[ Vapour Pressure ]:
1.23E-12mmHg at 25°C


Related Compounds