Vanilpyruvic acid

Vanilpyruvic acid is a catecholamine metabolite and precursor to vanillactic acid.

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Signaling Pathways >> Membrane Transporter/Ion Channel >> Monoamine Transporter

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

The catecholamines, dopamine, norepinephrine, and epinephrine, constitute a class of chemical neurotransmitters and hormones that occupy key positions in the regulation of physiological processes and the development of neurological, psychiatric, endocrine, and cardiovascular diseases[1]. Catecholamines, namely dopamine (3,4-dihydrophenylethylamine), norepinephrine (noradrenaline) and epinephrine (adrenaline), act as neurotransmitters or hormones at central and peripheral levels. In addition to being the most abundant of the monoamine neurotransmitters, dopamine is also found in non-neuronal tissues such as the gastrointestinal tract and the kidney, where it participates in the regulation of sodium balance[2].

[1]. Eisenhofer G, et al. Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacol Rev. 2004 Sep;56(3):331-49.

[2]. Bicker J, et al. Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples--a review. Anal Chim Acta. 2013 Mar 20;768:12-34.

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | Adrenaline | PZM-21 | Ivabradine hydrochloride | Prazosin hydrochloride | Clenbuterol hydrochloride | Loperamide hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | Oliceridine hydrochloride | pimozide | Reserpine