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Isomeranzin

Names

[ CAS No. ]:
1088-17-1

[ Name ]:
Isomeranzin

[Synonym ]:
7-Methoxy-8-(3-methyl-2-oxobutyl)-2H-chromen-2-one
iso-Meranzin
2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-oxobutyl)-

Biological Activity

[Description]:

Isomerazin is a coumarin isolated from Poncirus trifoliate Raf., and shows cholinesterase inhibition[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Pokharel YR, et al. Potent protective effect of isoimperatorin against aflatoxin B1-inducible cytotoxicity in H4IIE cells: bifunctional effects on glutathione S-transferase and CYP1A. Carcinogenesis. 2006 Dec;27(12):2483-90.

[2]. Renata P. dos Santos,et al. Chemical composition and biological activity of leaves and fruits of Triphasia trifolia. Química Nova 31(1):53-58 • December 2007.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
423.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H16O4

[ Molecular Weight ]:
260.285

[ Flash Point ]:
188.9±28.8 °C

[ Exact Mass ]:
260.104858

[ PSA ]:
56.51000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.545

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932209090

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%