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Chrysotobibenzyl

Names

[ CAS No. ]:
108853-09-4

[ Name ]:
Chrysotobibenzyl

[Synonym ]:
Aloifol II dimethyl ether
3,3',4,4',5-pentamethoxybibenzyl
3,4,5,3',4'-pentamethoxybibenzyl
Benzene,5-(2-(3,4-dimethoxyphenyl)ethyl)-1,2,3-trimethoxy
gastrochilinin
Chrysotobibenzyl

Biological Activity

[Description]:

Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin (HY-17394)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Petpiroon N, et al. Chrysotobibenzyl inhibition of lung cancer cell migration through Caveolin-1-dependent mediation of the integrin switch and the sensitization of lung cancer cells to cisplatin-mediated apoptosis. Phytomedicine. 2019 May;58:152888.  

Chemical & Physical Properties

[ Density]:
1.097g/cm3

[ Boiling Point ]:
422.3ºC at 760mmHg

[ Molecular Formula ]:
C19H24O5

[ Molecular Weight ]:
332.39

[ Flash Point ]:
167.6ºC

[ Exact Mass ]:
332.16200

[ PSA ]:
46.15000

[ LogP ]:
3.51480

[ Vapour Pressure ]:
6.01E-07mmHg at 25°C

[ Index of Refraction ]:
1.53

Related Compounds