Pyridin-3-ol

Names

[ CAS No. ]:
109-00-2

[ Name ]:
Pyridin-3-ol

[Synonym ]:
β-Hydroxypyridine
m-Hydroxypyridine
2-PYRIDON
3-Pyridinol
3-PYRIDOL
EINECS 205-520-3
T6NJ CQ
3-Pyridinol,3-Pyridone
3-HP
3-pyridinylphenol
pyridin-3-ol
B-PYRIDONE
3-Pyridyl alcohol
3-Oxopyridine
3-OH-pyridine
3-hydroxy-pyridine
3-PYRIDONE
MFCD00006268

Biological Activity

[Description]:

3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Atsushi Endo, et al. Bamboo grass extract and use of the same extract. JP2006298766A

[2]. L D Lukyanova, et al. Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. Bull Exp Biol Med. 2009 Oct;148(4):587-91.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
318.9±0.0 °C at 760 mmHg

[ Melting Point ]:
125-128 °C(lit.)

[ Molecular Formula ]:
C₅H₅NO

[ Molecular Weight ]:
95.099

[ Flash Point ]:
146.6±20.4 °C

[ Exact Mass ]:
95.037117

[ PSA ]:
33.12000

[ LogP ]:
0.64

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7701400

CHEMICAL NAME :: 3-Pyridinol

CAS REGISTRY NUMBER :: 109-00-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H5-N-O

MOLECULAR WEIGHT :: 95.11

WISWESSER LINE NOTATION :: T6NJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1822 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,259,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UV1144050

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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