5-DIMETHYLAMINONAPHTHALENE-1-SULFONYL-GLYCINE

Names

[ Name ]:
5-DIMETHYLAMINONAPHTHALENE-1-SULFONYL-GLYCINE

[Synonym ]:
N-[5-(Dimethylamino)naphthalene-1-sulfonyl]glycine
2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]acetic acid
MFCD00037734

Biological Activity

[Description]:

Dansylglycine is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.381g/cm3

[ Boiling Point ]:
525.7ºC at 760mmHg

[ Melting Point ]:
159ºC

[ Molecular Formula ]:
C₁₄H₁₆N₂O₄S

[ Molecular Weight ]:
308.35300

[ Flash Point ]:
271.7ºC

[ Exact Mass ]:
308.08300

[ PSA ]:
95.09000

[ LogP ]:
2.74040

[ Vapour Pressure ]:
7.01E-12mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Phase separation kinetics in amorphous solid dispersions upon exposure to water.

Mol. Pharm. 12 , 1623-35, (2015)

The purpose of this study was to develop a novel fluorescence technique employing environment-sensitive fluorescent probes to study phase separation kinetics in hydrated matrices of amorphous solid di...

Interactions of the carrier ligands of antidiabetic metal complexes with human serum albumin: a combined spectroscopic and separation approach with molecular modeling studies.

Bioorg. Med. Chem. 19 , 4202-4210, (2011)

The specific binding of carrier ligands of antidiabetic vanadium(IV) and zinc(II) complexes into drug binding pockets of human serum albumin (HSA) has been investigated via displacement reactions of s...

Immobilized fluorescent cyclodextrin on a cellulose membrane as a chemosensor for molecule detection.

Anal. Chem. 73 , 3126-3130, (2001)

Dansylglycine-modified cyclodextrin (DnsC4-beta-CD) was prepared as a fluorescent host that is capable of being immobilized on a cellulose membrane (DnsC4-beta-CD membrane). DnsC4-beta-CD immobilized ...