<Suppliers Price>

CTP 518(Atazanavir, deuterated)

Names

[ CAS No. ]:
1092540-56-1

[ Name ]:
CTP 518(Atazanavir, deuterated)

[Synonym ]:
(H)Methyl [(5S,10S,11S,14S)-11-benzyl-10-hydroxy-15,15-bis[(H)methyl]-5-(2-methyl-2-propanyl)-3,6,13-trioxo-8-[4-(2-pyridinyl)benzyl](1,1,1,16,16,16-H)-2-oxa-4,7,8,12-tetraazahexadec &#xA;an-14-yl]carbamate
Butanoic acid, 3,3-dimethyl-2-[[(methyl-d-oxy)carbonyl]amino]-, 2-[(2S,3S)-3-[[(2S)-3,3-di(methyl-d)-2-[[(methyl-d-oxy)carbonyl]amino]-1-oxobutyl-4,4,4-d]amino]-2-hydroxy-4-phenylbutyl]-2-&#xD; [[4-(2-pyridinyl)phenyl]methyl]hydrazide, (2S)-
y0306

Biological Activity

[Description]:

Atazanavir-d15 is the d15 labled Atazanavir (HY-17367). Atazanavir is a selective HIV-1 protease inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[Target]

HIV-1


[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C38H37D15N6O7

[ Molecular Weight ]:
719.95

[ Exact Mass ]:
719.483887

[ PSA ]:
185.18000

[ LogP ]:
5.20

[ Index of Refraction ]:
1.562

Related Compounds