3-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4,5-d ihydro-1,3-thiazol-2-yl)benzamide
Names
[ CAS No. ]:
1092788-09-4
[ Name ]:
3-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4,5-d ihydro-1,3-thiazol-2-yl)benzamide
Biological Activity
[Description]:
PP30, a TORKinib, is a potent, selective, and ATP-competitive inhibitor of mTOR with an IC50 of 80 nM.
[Related Catalog]:
[Target]
p110δ:0.99 μM (IC50)
p110γ:0.68 μM (IC50)
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H19N7OS
[ Molecular Weight ]:
381.45500
[ Exact Mass ]:
381.13700
[ PSA ]:
139.87000
[ LogP ]:
3.08060