Methoxyl-d3-amine Hydrochloride

Names

[ Name ]:
Methoxyl-d3-amine Hydrochloride

[Synonym ]:
O-(trideuteriomethyl)hydroxylamine,hydrochloride

Biological Activity

[Description]:

Methoxyamine-d3 (Hydrochloride) is the deuterium labeled Methoxyamine hydrochloride[1]. Methoxyamine (O-Methylhydroxylamine) hydrochloride is a reagent in the preparation of O-methyl oximes or synthesis of O-methyl oximes from aldehydes[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Sear JW, et al. Plasma concentrations of alphaxalone by gas chromatography: comparison with other gas chromatographic methods and gas chromatography-mass spectrometry. J Pharm Pharmacol. 1980 May;32(5):349-52.

Chemical & Physical Properties

[ Molecular Formula ]:
CH₃ClD₃NO

[ Molecular Weight ]:
86.53590

[ Exact Mass ]:
86.03260

[ PSA ]:
35.25000

[ LogP ]:
1.00880

Methoxyl-d3-amine Hydrochloride

Names

Biological Activity

Chemical & Physical Properties

Related Compounds