(R)-Exatecan Intermediate 1
Names
[ CAS No. ]:
110351-91-2
[ Name ]:
(R)-Exatecan Intermediate 1
[Synonym ]:
(4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
.5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]
Biological Activity
[Description]:
(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].
[Related Catalog]:
Chemical & Physical Properties
[ Molecular Formula ]:
C13H13NO5
[ Molecular Weight ]:
263.25
[ Exact Mass ]:
263.07900
[ PSA ]:
85.60000
[ LogP ]:
0.08910