2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid

Names

[ Name ]:
2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid

Biological Activity

[Description]:

Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7.

[2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₁₀N₂O₄

[ Molecular Weight ]:
186.17

[ Storage condition ]:
2-8℃