propaquizafop

Names

[ Name ]:
propaquizafop

[Synonym ]:
2-[[(1-methylethylidene)amino]oxy]ethyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate
Propanoic acid,2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-,2-(((1-methylethylidene)amino)oxy)ethyl ester,(R)
(R)-2-[[(1-Methylethylidene)amino]oxy]ethyl 2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate
Shogun
Propanoic acid, 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-, 2-(((1-methylethylidene)amino)oxy)ethyl ester, (R)-
Propaquizafop [ISO]
2-isopropylideneaminooxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate
2-[(Isopropylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
propaquizafop
2-[(Propan-2-ylidenamino)oxy]ethyl-(2R)-2-{4-[(6-chlorchinoxalin-2-yl)oxy]phenoxy}propanoat
2-Isopropylideneamino-oxyethyl (R)-2-(4-(6-chloroquinoxalin-2-yloxy)phenoxy)propionate
Ro 17-3664
2-{[(propan-2-ylidene)amino]oxy}ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
2-Isopropylideneamino-oxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate
2-[(Isopropylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy}propanoate
Propanoic acid, 2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]-, 2-[[(1-methylethylidene)amino]oxy]ethyl ester, (2R)-
2-(propan-2-ylideneamino)oxyethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate
AGIL
2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
2-[(2-Propanylidenamino)oxy]ethyl-(2R)-2-{4-[(6-chlor-2-chinoxalinyl)oxy]phenoxy}propanoat
(2R)-2-{4-[(6-Chloro-2-quinoxalinyl)oxy]phénoxy}propanoate de 2-[(isopropylidéneamino)oxy]éthyle

Biological Activity

[Description]:

Propaquizafop is a phenoxyisopropionic acid herbicide and an acetyl-coA carboxylase inhibitor[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Acetyl-CoA Carboxylase

[References]

[1]. Bouis, et al. Effect of Propaquizafop and Its Free-Acid Derivative on Lauric Acid Hydroxylation and Peroxisomal Beta-Oxidation in Primary Cultured Rat, Mouse, Guinea Pig and Marmoset Hepatocytes. Toxicol In Vitro. 1993 Jul;7(4):427-31.

[2]. Laura R Davies, et al. Detection and Characterization of Resistance to Acetolactate Synthase Inhibiting Herbicides in Anisantha and Bromus Species in the United Kingdom. Pest Manag Sci. 2020 Jul;76(7):2473-2482.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
582.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₂ClN₃O₅

[ Molecular Weight ]:
443.880

[ Flash Point ]:
306.2±32.9 °C

[ Exact Mass ]:
443.124786

[ PSA ]:
92.13000

[ LogP ]:
5.24

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.587

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA2458258

CHEMICAL NAME :: Propanoic acid, 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-, 2-(((1-methylethylidene)amino) oxy)ethyl ester, (R)-

CAS REGISTRY NUMBER :: 111479-05-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H22-Cl-N3-O5

MOLECULAR WEIGHT :: 443.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,718,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H332

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20

[ Safety Phrases ]:
S22

[ RIDADR ]:
NONH for all modes of transport