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ganodermic acid S

Names

[ CAS No. ]:
112430-63-4

[ Name ]:
ganodermic acid S

[Synonym ]:
Lanosta-7,9(11),24-trien-3,15-diacetoxy-26-oic acid
Ganoderic acid R
Ganodermic acid S
Lanosta-7,9(11),24-trien-26-oic acid,3,15-bis(acetyloxy)-,(3beta,15alpha,24E)

Biological Activity

[Description]:

Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[References]

[1]. Su CY, et al. Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets. Biochem Pharmacol. 1999 Aug 15;58(4):587-95.  

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
633.8ºC at 760mmHg

[ Molecular Formula ]:
C34H50O6

[ Molecular Weight ]:
554.75700

[ Flash Point ]:
191.1ºC

[ Exact Mass ]:
554.36100

[ PSA ]:
89.90000

[ LogP ]:
7.43220

[ Vapour Pressure ]:
1.08E-17mmHg at 25°C

[ Index of Refraction ]:
1.544

Related Compounds