6-JOE SE

Names

[ Name ]:
6-JOE SE

[Synonym ]:
6-Joe,SE [6-Carboxy-4',5'-Dichloro-2',7'-Dimethoxyfluorescein,Succinimidyl Ester]
6-JOE SE
6-Carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein N-hydroxysuccinimide ester
2,5-Dioxopyrrolidin-1-yl 4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylate

Biological Activity

[Description]:

6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tsybulsky DA, et al. 4',5'-Dichloro-2',7'-dimethoxy-5(6)-carboxyfluorescein (JOE): synthesis and spectral properties of oligonucleotide conjugates. J Org Chem. 2012 Jan 20;77(2):977-84.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₁₇Cl₂NO₁₁

[ Molecular Weight ]:
602.33000

[ Exact Mass ]:
601.01800

[ PSA ]:
158.13000

[ LogP ]:
4.14850

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport