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Z-AEVD-FMK

Names

[ CAS No. ]:
1135688-47-9

[ Name ]:
Z-AEVD-FMK

[Synonym ]:
Methyl (5S,8S,11S,14S)-14-(fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate

Biological Activity

[Description]:

Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
883.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H39FN4O10

[ Molecular Weight ]:
610.628

[ Flash Point ]:
488.3±34.3 °C

[ Exact Mass ]:
610.265015

[ LogP ]:
3.62

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.512

Related Compounds